- Eli McGee, RB, lugoff-Elgin 104 yards rushing
- Jy tolen, QB, Gilbert – passed for 358 yards and four TDs and rushed for one TD
- Dre Cook, RB, Gilbert – rushed for 102 yds and 2 TDs
- Ty Walker, RB, Gilbert – rushed for 143 yds and 2 TDs
- KZ Adams, RB Gray – rushed for 122 yds, 102 yds receiving and scored four TDs
- Hunter Helms, QB, Gray – passed for 355 yds 2 TDs
- Ahmad Byneim-Scott, RB, Lexington – rushed for 140 yds, 1 TD in win over Irmo
- Levi Gulasa, LB, Lexington – INT for 36 yds pick-6 to seal the game against Irmo
- Jackson Stone, QB, River Bluff – passed for 2 TDs and rushed for 1 TD in win over Fort Mill
- Willis Lane, RB, Camden – rushed for 221 yds and 5 TDs in win over North Central
- Jaffari Pearson, QB, Camden – rushed for 2 TDs and ran for 1TD
- Matt Pack, RB, AC Flora – rushed for 126 yds and 1 TD in win over Beaufort
- Shanye Monsanto, RB, Cardinal Newman – ran for 3 TDs in win over John Pall II
- Jake Cowen, QB, Cardinal Newman – passed for 128 yds and two TDs
- Will Taylor, QB, Ben Lippen – rushed for 131 yds and 3 TDs in win over Pinewood Prep
- Demondre Anderson, QB, AC Flora – rushed for 122 yards in loss to Great Falls
- Bruce Staley, RB, Airport – rushed for 219 yds and 2 TDs in win over Dreher
- Nanders Lawrence, RB, Airport – rushed for 139 yds and 2 TDs
- Ty Olenchuk, QB, Dutch Fork – passed for 295 yds and 4 TDs in tie against Mallard Creek
- JaylinHyatt, WR, Dutch Fork – 4 receptions and 3 TDs
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